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Protocol for a feasibility randomized controlled trial to evaluate the efficacy, safety and tolerability of N-acetylcysteine in reducing adverse drug reactions among adults treated for multidrug-resistant tuberculosis in Tanzania

BACKGROUND: Adverse drug reactions (ADRs) frequently occur in patients using second-line anti-tuberculosis medicine for treatment of multidrug resistant tuberculosis (MDR-TB). ADRs contribute to treatment interruptions which can compromise treatment response and risk acquired drug resistance to crit...

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Detalles Bibliográficos
Autores principales: Mpagama, Stellah G., Mvungi, Happiness C., Mbelele, Peter M., Semvua, Hadija H., Liyoyo, Alphonce A., de Guex, Kristen Petros, Sloan, Derek, Kibiki, Gibson S., Boeree, Martin, Phillips, Patrick P. J., Heysell, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066962/
https://www.ncbi.nlm.nih.gov/pubmed/37005695
http://dx.doi.org/10.1186/s40814-023-01281-7