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KIAA1429 mediates epithelial mesenchymal transition in sorafenib‐resistant hepatocellular carcinoma through m6A methylation modification

BACKGROUND: Hepatocellular carcinoma (HCC) is a primary liver cancer with high mortality. The long‐term use of sorafenib, a targeted drug for hepatocellular carcinoma, will lead to drug resistance, and patients are prone to cancer metastasis, the molecular mechanism of which is still unclear. METHOD...

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Detalles Bibliográficos
Autores principales: Kuang, Ye, Cheng, Yun, Wang, Jia, Li, Hongyan, Cao, Xianghong, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067093/
https://www.ncbi.nlm.nih.gov/pubmed/36420693
http://dx.doi.org/10.1002/cam4.5432