Cargando…

KIAA1429 mediates epithelial mesenchymal transition in sorafenib‐resistant hepatocellular carcinoma through m6A methylation modification

BACKGROUND: Hepatocellular carcinoma (HCC) is a primary liver cancer with high mortality. The long‐term use of sorafenib, a targeted drug for hepatocellular carcinoma, will lead to drug resistance, and patients are prone to cancer metastasis, the molecular mechanism of which is still unclear. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuang, Ye, Cheng, Yun, Wang, Jia, Li, Hongyan, Cao, Xianghong, Wang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067093/ https://www.ncbi.nlm.nih.gov/pubmed/36420693 http://dx.doi.org/10.1002/cam4.5432

Ejemplares similares

KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA
por: Cheng, Xiaoyu, et al.
Publicado: (2019)

KIAA1429 facilitates progression of hepatocellular carcinoma by modulating m6A levels in HPN
por: Meng, Yu, et al.
Publicado: (2023)

KIAA1429 regulates alternative splicing events of cancer-related genes in hepatocellular carcinoma
por: Liu, Zhao-chen, et al.
Publicado: (2022)

KIAA1429 promotes infantile hemangioma regression by facilitating the stemness of hemangioma endothelial cells
por: Wang, Luying, et al.
Publicado: (2023)

m6A ‘writer’ KIAA1429 regulates the proliferation and migration of endothelial cells in atherosclerosis
por: Rong, Jian, et al.
Publicado: (2022)

The biological function of m6A methyltransferase KIAA1429 and its role in human disease
por: Zhang, Xiaoyu, et al.
Publicado: (2022)

KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3
por: Lan, Tian, et al.
Publicado: (2019)

KIAA1217 Promotes Epithelial-Mesenchymal Transition and Hepatocellular Carcinoma Metastasis by Interacting with and Activating STAT3
por: Wang, Yanhong, et al.
Publicado: (2021)

CRISPR-Cas9 knockout screening identifies KIAA1429 as an essential gene in Ewing sarcoma
por: Tan, Kezhe, et al.
Publicado: (2023)

KIAA1429-mediated m6A modification of CHST11 promotes progression of diffuse large B-cell lymphoma by regulating Hippo–YAP pathway
por: Chen, Xiaomin, et al.
Publicado: (2023)

The role and mechanism of JAK2/STAT3 signaling pathway regulated by m6A methyltransferase KIAA1429 in osteosarcoma
por: Luo, Jiaquan, et al.
Publicado: (2023)

KIAA1429/VIRMA promotes breast cancer progression by m(6)A‐dependent cytosolic HAS2 stabilization
por: Li, Na, et al.
Publicado: (2023)

m(6)A methyltransferase KIAA1429 accelerates oral squamous cell carcinoma via regulating glycolysis and ferroptosis
por: Xu, Ke, et al.
Publicado: (2023)

SMC1A regulated by KIAA1429 in m6A-independent manner promotes EMT progress in breast cancer
por: Zhang, Xu, et al.
Publicado: (2021)

Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
por: Deng, Yan-Ru, et al.
Publicado: (2016)

N(6)-methyladenosine (m(6)A) methyltransferase KIAA1429 accelerates the gefitinib resistance of non-small-cell lung cancer
por: Tang, Jun, et al.
Publicado: (2021)

N(6)-methyladenosine methyltransferase KIAA1429 elevates colorectal cancer aerobic glycolysis via HK2-dependent manner
por: Li, Ying, et al.
Publicado: (2022)

Pan-cancer analysis and experimental validation revealed the m6A methyltransferase KIAA1429 as a potential biomarker for diagnosis, prognosis, and immunotherapy
por: Ma, Chao, et al.
Publicado: (2023)

m(6)A Methyltransferase KIAA1429 Regulates the Cisplatin Sensitivity of Gastric Cancer Cells via Stabilizing FOXM1 mRNA
por: Zhu, Zhongcheng, et al.
Publicado: (2022)

KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition
por: Zhang, Tao, et al.
Publicado: (2019)

N6-methyladenosine methyltransferase KIAA1429 promoted ovarian cancer aerobic glycolysis and progression through enhancing ENO1 expression
por: Gan, Lijuan, et al.
Publicado: (2023)

Promotive role of USP29-mediated deubiquitination in malignant proliferation of colorectal cancer cells via the KIAA1429/SOX8 axis
por: Li, Juncai, et al.
Publicado: (2023)

The m(6)A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy
por: Yao, Fangyi, et al.
Publicado: (2023)

m(6)A methyltransferase KIAA1429 acts as an oncogenic factor in colorectal cancer by regulating SIRT1 in an m(6)A-dependent manner
por: Zhou, Yuan, et al.
Publicado: (2022)

N6-methyladenine- induced LINC00667 promoted breast cancer progression through m6A/KIAA1429 positive feedback loop
por: Ren, Saiyu, et al.
Publicado: (2022)

Sorafenib suppresses the epithelial-mesenchymal transition of hepatocellular carcinoma cells after insufficient radiofrequency ablation
por: Dong, Shuying, et al.
Publicado: (2015)

Regorafenib reverses HGF‐induced sorafenib resistance by inhibiting epithelial‐mesenchymal transition in hepatocellular carcinoma
por: Chen, Weibo, et al.
Publicado: (2019)

Gene amplification‐driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A‐YTHDF2‐dependent in lung adenocarcinoma
por: Zhang, Chang, et al.
Publicado: (2022)

KPNA3 Confers Sorafenib Resistance to Advanced Hepatocellular Carcinoma via TWIST Regulated Epithelial-Mesenchymal Transition
por: Hu, Bo, et al.
Publicado: (2019)

KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation
por: Hua, Qingling, et al.
Publicado: (2023)

Upregulation of PD-L1 expression promotes epithelial-to-mesenchymal transition in sorafenib-resistant hepatocellular carcinoma cells
por: Xu, Gui-Li, et al.
Publicado: (2020)

Corrigendum to: Regorafenib reverses HGF‐induced sorafenib resistance by inhibiting epithelial‐mesenchymal transition in hepatocellular carcinoma
Publicado: (2022)

KIAA1429 and ALKBH5 Oppositely Influence Aortic Dissection Progression via Regulating the Maturation of Pri-miR-143-3p in an m6A-Dependent Manner
por: Wang, Peng, et al.
Publicado: (2021)

Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial–mesenchymal transition
por: Liu, Jingmei, et al.
Publicado: (2023)

SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
por: Wang, Shanshan, et al.
Publicado: (2023)

Y-Box Binding Protein-1 Promotes Epithelial-Mesenchymal Transition in Sorafenib-Resistant Hepatocellular Carcinoma Cells
por: Liao, Li-Zhu, et al.
Publicado: (2020)

Pinin Induces Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma by Regulating m6A Modification
por: Qiao, Kailiang, et al.
Publicado: (2021)

KIAA1199, a Target of MicoRNA-486-5p, Promotes Papillary Thyroid Cancer Invasion by Influencing Epithelial-Mesenchymal Transition (EMT)
por: Jiao, Xuehua, et al.
Publicado: (2019)

LncRNA LIMT (LINC01089) contributes to sorafenib chemoresistance via regulation of miR-665 and epithelial to mesenchymal transition in hepatocellular carcinoma cells: LIMT contributes to sorafenib chemoresistance in HCC
por: Sun, Jing, et al.
Publicado: (2021)

Sorafenib Inhibits Epithelial-Mesenchymal Transition through an Epigenetic-Based Mechanism in Human Lung Epithelial Cells
por: Zhang, Juyong, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_go3mqf1aatr8e81gp00lvqiv8k