Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer’s disease brain

Loss of synapses is the most robust pathological correlate of Alzheimer’s disease (AD)-associated cognitive deficits, although the underlying mechanism remains incompletely understood. Synaptic terminals have abundant mitochondria which play an indispensable role in synaptic function through ATP pro...

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Detalles Bibliográficos
Autores principales: Wang, Wenzhang, Zhao, Fanpeng, Lu, Yubing, Siedlak, Sandra L., Fujioka, Hisashi, Feng, Hao, Perry, George, Zhu, Xiongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067183/
https://www.ncbi.nlm.nih.gov/pubmed/37004141
http://dx.doi.org/10.1186/s40478-023-01552-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067183/
https://www.ncbi.nlm.nih.gov/pubmed/37004141
http://dx.doi.org/10.1186/s40478-023-01552-7

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