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Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer’s disease brain
Loss of synapses is the most robust pathological correlate of Alzheimer’s disease (AD)-associated cognitive deficits, although the underlying mechanism remains incompletely understood. Synaptic terminals have abundant mitochondria which play an indispensable role in synaptic function through ATP pro...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067183/ https://www.ncbi.nlm.nih.gov/pubmed/37004141 http://dx.doi.org/10.1186/s40478-023-01552-7 |