Enrichment of miR-17-5p enhances the protective effects of EPC-EXs on vascular and skeletal muscle injury in a diabetic hind limb ischemia model

BACKGROUND/AIMS: Diabetes mellitus (DM) is highly susceptible to diabetic hind limb ischemia (DHI). MicroRNA (MiR)-17-5p is downregulated in DM and plays a key role in vascular protection. Endothelial progenitor cell (EPC)-released exosomes (EPC-EXs) contribute to vascular protection and ischemic ti...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Qunwen, Xu, Xiaobing, He, Wen, Wang, Yan, Xiang, Zhi, Jin, Xiaojuan, Tang, Qiong, Zhao, Ting, Ma, Xiaotang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067242/
https://www.ncbi.nlm.nih.gov/pubmed/37005678
http://dx.doi.org/10.1186/s40659-023-00418-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067242/
https://www.ncbi.nlm.nih.gov/pubmed/37005678
http://dx.doi.org/10.1186/s40659-023-00418-5

Ejemplares similares