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FTO-mediated m6A demethylation of pri-miR-3591 alleviates osteoarthritis progression

OBJECTIVES: Increasing evidence have demonstrated the N6-methyladenosine (m(6)A) plays critical roles in osteoarthritis (OA) progression, but the role of m(6)A in OA has not been completely illuminated. Herein, we investigated the function and underlying mechanism of m(6)A demethylase fat mass and o...

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Detalles Bibliográficos
Autores principales: Liu, Wengang, Jiang, Tao, Zheng, Wei, Zhang, Jiayuan, Li, Anan, Lu, Chao, Lin, Zhaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067311/
https://www.ncbi.nlm.nih.gov/pubmed/37005694
http://dx.doi.org/10.1186/s13075-023-03035-5