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Association of KMT2C/D loss‐of‐function variants with response to immune checkpoint blockades in colorectal cancer

Immune checkpoint inhibitors (ICIs) have become important treatment strategies, yet responses vary among patients and predictive biomarkers are urgently needed. Mutations in KMT2C and KMT2D lead to increased levels of genomic instability. Therefore, we aimed to examine whether KMT2C/D mutations migh...

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Detalles Bibliográficos
Autores principales: Liu, Ruiqi, Niu, Yanling, Liu, Chao, Zhang, Xin, Zhang, Jinku, Shi, Min, Zou, Wenbo, Gu, Binbin, Zhu, Honglin, Wang, Danhua, Yuan, Hongling, Li, Wei, Zhao, Dandan, Zheng, Qiaosong, Liu, Rong, Chen, Weiping, Ma, Tonghui, Zhang, Yanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067420/
https://www.ncbi.nlm.nih.gov/pubmed/36601880
http://dx.doi.org/10.1111/cas.15716