BRCA1 haploinsufficiency impairs iron metabolism to promote chrysotile‐induced mesothelioma via ferroptosis resistance

Malignant mesothelioma (MM) is still a social burden associated with asbestos exposure. Local iron accumulation thereby represents the major pathogenesis, followed by oxidative DNA strand breaks and genomic alterations in the mesothelium. BRCA1 is a critical component of homologous recombination rep...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Yaguang, Akatsuka, Shinya, Motooka, Yashiro, Kong, Yingyi, Zheng, Hao, Mashimo, Tomoji, Imaoka, Tatsuhiko, Toyokuni, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067434/
https://www.ncbi.nlm.nih.gov/pubmed/36541514
http://dx.doi.org/10.1111/cas.15705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067434/
https://www.ncbi.nlm.nih.gov/pubmed/36541514
http://dx.doi.org/10.1111/cas.15705

Ejemplares similares