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In vivo quantitative high-throughput screening for drug discovery and comparative toxicology

Quantitative high-throughput screening (qHTS) pharmacologically evaluates chemical libraries for therapeutic uses, toxicological risk and, increasingly, for academic probe discovery. Phenotypic high-throughput screening assays interrogate molecular pathways, often relying on cell culture systems, hi...

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Detalles Bibliográficos
Autores principales: Dranchak, Patricia K., Oliphant, Erin, Queme, Bryan, Lamy, Laurence, Wang, Yuhong, Huang, Ruili, Xia, Menghang, Tao, Dingyin, Inglese, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067442/
https://www.ncbi.nlm.nih.gov/pubmed/36786055
http://dx.doi.org/10.1242/dmm.049863