Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses

Subunit vaccines typically require co-administration with an adjuvant to elicit protective immunity, adding development hurdles that can impede rapid pandemic responses. To circumvent the need for adjuvant in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subunit vaccine, we engineer...

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Detalles Bibliográficos
Autores principales: Kassardjian, Audrey, Sun, Eric, Sookhoo, Jamie, Muthuraman, Krithika, Boligan, Kayluz Frias, Kucharska, Iga, Rujas, Edurne, Jetha, Arif, Branch, Donald R., Babiuk, Shawn, Barber, Brian, Julien, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067452/
https://www.ncbi.nlm.nih.gov/pubmed/37053069
http://dx.doi.org/10.1016/j.celrep.2023.112391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067452/
https://www.ncbi.nlm.nih.gov/pubmed/37053069
http://dx.doi.org/10.1016/j.celrep.2023.112391

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