Nicotinamide Phosphoribosyltransferase‐elevated NAD(+) biosynthesis prevents muscle disuse atrophy by reversing mitochondrial dysfunction

BACKGROUND: It is well known that muscle disuse atrophy is associated with mitochondrial dysfunction, which is implicated in reduced nicotinamide adenine dinucleotide (NAD(+)) levels. Nicotinamide phosphoribosyltransferase (NAMPT), a rate‐limiting enzyme in NAD(+) biosynthesis, may serve as a novel...

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Detalles Bibliográficos
Autores principales: Zhang, Yao, Wang, Yingming, Lu, Shuai, Zhong, Rui, Liu, Zhilin, Zhao, Qichun, Wang, Chongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067495/
https://www.ncbi.nlm.nih.gov/pubmed/36864250
http://dx.doi.org/10.1002/jcsm.13182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067495/
https://www.ncbi.nlm.nih.gov/pubmed/36864250
http://dx.doi.org/10.1002/jcsm.13182

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