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IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation
Intestinal epithelial cells (IECs) constitute a critical first line of defense against microbes. While IECs are known to respond to various microbial signals, the precise upstream cues regulating diverse IEC responses are not clear. Here, we discover a dual role for IEC-intrinsic interleukin-1 recep...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067527/ https://www.ncbi.nlm.nih.gov/pubmed/36976181 http://dx.doi.org/10.1084/jem.20212523 |