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IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation

Intestinal epithelial cells (IECs) constitute a critical first line of defense against microbes. While IECs are known to respond to various microbial signals, the precise upstream cues regulating diverse IEC responses are not clear. Here, we discover a dual role for IEC-intrinsic interleukin-1 recep...

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Detalles Bibliográficos
Autores principales:	Overcast, Garrett R., Meibers, Hannah E., Eshleman, Emily M., Saha, Irene, Waggoner, Lisa, Patel, Krupaben N., Jain, Viral G., Haslam, David B., Alenghat, Theresa, VanDussen, Kelli L., Pasare, Chandrashekhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067527/ https://www.ncbi.nlm.nih.gov/pubmed/36976181 http://dx.doi.org/10.1084/jem.20212523

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