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DAB2 promotes pulmonary fibrosis and may act as an intermediate between IGF‑1R and PI3K/AKT signaling pathways

Idiopathic pulmonary fibrosis (IPF) is a heterogeneous lung disease associated with high mortality. Disabled-2 (DAB2), an adapter protein, regulates cell-fibrinogen adhesion and fibrinogen uptake. DAB2 is differentially expressed in mouse fibrotic lungs induced by bleomycin according to a genome mic...

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Detalles Bibliográficos
Autores principales: Liang, Chun-Lian, Li, Xiu-Li, Quan, Xiao-Juan, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067542/
https://www.ncbi.nlm.nih.gov/pubmed/37021069
http://dx.doi.org/10.3892/etm.2023.11882