Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling

Objective: Synovitis and fibrosis are common pathological features of knee osteoarthritis (KOA). The interaction of synovitis and fibrosis can promote KOA progression. Chrysin (CHR), a natural flavonoid, may treat inflammation and prevent fibrosis. However, the effect and mechanism of CHR in KOA syn...

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Detalles Bibliográficos
Autores principales: Ding, Liang, Liao, Taiyang, Yang, Nan, Wei, Yibao, Xing, Runlin, Wu, Peng, Li, Xiaochen, Mao, Jun, Wang, Peimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067567/
https://www.ncbi.nlm.nih.gov/pubmed/37021049
http://dx.doi.org/10.3389/fphar.2023.1170243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067567/
https://www.ncbi.nlm.nih.gov/pubmed/37021049
http://dx.doi.org/10.3389/fphar.2023.1170243

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