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Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling

Objective: Synovitis and fibrosis are common pathological features of knee osteoarthritis (KOA). The interaction of synovitis and fibrosis can promote KOA progression. Chrysin (CHR), a natural flavonoid, may treat inflammation and prevent fibrosis. However, the effect and mechanism of CHR in KOA syn...

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Detalles Bibliográficos
Autores principales:	Ding, Liang, Liao, Taiyang, Yang, Nan, Wei, Yibao, Xing, Runlin, Wu, Peng, Li, Xiaochen, Mao, Jun, Wang, Peimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067567/ https://www.ncbi.nlm.nih.gov/pubmed/37021049 http://dx.doi.org/10.3389/fphar.2023.1170243

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