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Machine learning meets Monte Carlo methods for models of muscle’s molecular machinery to classify mutations
The timing and magnitude of force generation by a muscle depend on complex interactions in a compliant, contractile filament lattice. Perturbations in these interactions can result in cardiac muscle diseases. In this study, we address the fundamental challenge of connecting the temporal features of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067704/ https://www.ncbi.nlm.nih.gov/pubmed/37000171 http://dx.doi.org/10.1085/jgp.202213291 |