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Machine learning meets Monte Carlo methods for models of muscle’s molecular machinery to classify mutations

The timing and magnitude of force generation by a muscle depend on complex interactions in a compliant, contractile filament lattice. Perturbations in these interactions can result in cardiac muscle diseases. In this study, we address the fundamental challenge of connecting the temporal features of...

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Detalles Bibliográficos
Autores principales: Asencio, Anthony, Malingen, Sage, Kooiker, Kristina B., Powers, Joseph D., Davis, Jennifer, Daniel, Thomas, Moussavi-Harami, Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067704/
https://www.ncbi.nlm.nih.gov/pubmed/37000171
http://dx.doi.org/10.1085/jgp.202213291