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Thin filament regulation of cardiac muscle power output: Implications for targets to improve human failing hearts

The heart’s pumping capacity is determined by myofilament power generation. Power is work done per unit time and measured as the product of force and velocity. At a sarcomere level, these contractile properties are linked to the number of attached cross-bridges and their cycling rate, and many signa...

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Detalles Bibliográficos
Autores principales: Hanft, Laurin M., Robinett, Joel C., Kalogeris, Theodore J., Campbell, Kenneth S., Biesiadecki, Brandon J., McDonald, Kerry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067705/
https://www.ncbi.nlm.nih.gov/pubmed/37000170
http://dx.doi.org/10.1085/jgp.202213290