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Thin filament regulation of cardiac muscle power output: Implications for targets to improve human failing hearts
The heart’s pumping capacity is determined by myofilament power generation. Power is work done per unit time and measured as the product of force and velocity. At a sarcomere level, these contractile properties are linked to the number of attached cross-bridges and their cycling rate, and many signa...
Autores principales: | Hanft, Laurin M., Robinett, Joel C., Kalogeris, Theodore J., Campbell, Kenneth S., Biesiadecki, Brandon J., McDonald, Kerry S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067705/ https://www.ncbi.nlm.nih.gov/pubmed/37000170 http://dx.doi.org/10.1085/jgp.202213290 |
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