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Umbelliferone Ameliorates Hepatic Steatosis and Lipid-Induced ER Stress in High-Fat Diet-Induced Obese Mice

PURPOSE: Among the characteristics of non-alcoholic fatty liver disease (NAFLD), hepatic steatosis is due to excessive fat accumulation and causes liver damage and lipotoxicity, which are associated with insulin resistance, endoplasmic reticulum (ER) stress, and apoptosis. Umbelliferone (UMB) has va...

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Detalles Bibliográficos
Autores principales: Park, Na Won, Lee, Eun Soo, Ha, Kyung Bong, Jo, Su Ho, Kim, Hong Min, Kwon, Mi-Hye, Chung, Choon Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067795/
https://www.ncbi.nlm.nih.gov/pubmed/36996895
http://dx.doi.org/10.3349/ymj.2022.0354