Cargando…

Channel activity of SARS-CoV-2 viroporin ORF3a inhibited by adamantanes and phenolic plant metabolites

SARS-CoV-2 has been responsible for the major worldwide pandemic of COVID-19. Despite the enormous success of vaccination campaigns, virus infections are still prevalent and effective antiviral therapies are urgently needed. Viroporins are essential for virus replication and release, and are thus pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Fam, Marina Sherif, Sedky, Christine Adel, Turky, Nancy Osama, Breitinger, Hans-Georg, Breitinger, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067842/
https://www.ncbi.nlm.nih.gov/pubmed/37005439
http://dx.doi.org/10.1038/s41598-023-31764-9