Cargando…
Channel activity of SARS-CoV-2 viroporin ORF3a inhibited by adamantanes and phenolic plant metabolites
SARS-CoV-2 has been responsible for the major worldwide pandemic of COVID-19. Despite the enormous success of vaccination campaigns, virus infections are still prevalent and effective antiviral therapies are urgently needed. Viroporins are essential for virus replication and release, and are thus pr...
Autores principales: | Fam, Marina Sherif, Sedky, Christine Adel, Turky, Nancy Osama, Breitinger, Hans-Georg, Breitinger, Ulrike |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067842/ https://www.ncbi.nlm.nih.gov/pubmed/37005439 http://dx.doi.org/10.1038/s41598-023-31764-9 |
Ejemplares similares
-
Patch-clamp studies and cell viability assays suggest a distinct site for viroporin inhibitors on the E protein of SARS-CoV-2
por: Breitinger, Ulrike, et al.
Publicado: (2023) -
Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7
por: Mandour, Yasmine M, et al.
Publicado: (2018) -
Viroporins: Structure, function, and their role in the life cycle of SARS-CoV-2
por: Breitinger, Ulrike, et al.
Publicado: (2022) -
Inhibition of SARS CoV Envelope Protein by Flavonoids and Classical Viroporin Inhibitors
por: Breitinger, Ulrike, et al.
Publicado: (2021) -
Viroporins and inflammasomes: A key to understand virus-induced inflammation
por: Farag, N.S., et al.
Publicado: (2020)