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PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing

Two prominent concepts for the sensing of shear stress by endothelium are the PIEZO1 channel as a mediator of mechanically activated calcium ion entry and the PECAM1 cell adhesion molecule as the apex of a triad with CDH5 and VGFR2. Here, we investigated if there is a relationship. By inserting a no...

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Detalles Bibliográficos
Autores principales: Chuntharpursat-Bon, Eulashini, Povstyan, Oleksandr V., Ludlow, Melanie J., Carrier, David J., Debant, Marjolaine, Shi, Jian, Gaunt, Hannah J., Bauer, Claudia C., Curd, Alistair, Simon Futers, T., Baxter, Paul D., Peckham, Michelle, Muench, Stephen P., Adamson, Antony, Humphreys, Neil, Tumova, Sarka, Bon, Robin S., Cubbon, Richard, Lichtenstein, Laeticia, Beech, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067937/
https://www.ncbi.nlm.nih.gov/pubmed/37005489
http://dx.doi.org/10.1038/s42003-023-04706-4