Cargando…

Accessible light-controlled knockdown of cell-free protein synthesis using phosphorothioate-caged antisense oligonucleotides

Controlling cell-free expression of a gene to protein with non-invasive stimuli is vital to the future application of DNA nanodevices and synthetic cells. However, little emphasis has been placed on developing light-controlled ‘off’ switches for cell-free expression. Light-activated antisense oligon...

Descripción completa

Detalles Bibliográficos
Autores principales: Hartmann, Denis, Booth, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067960/
https://www.ncbi.nlm.nih.gov/pubmed/37005479
http://dx.doi.org/10.1038/s42004-023-00860-2