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BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy
The molecular basis of a severe developmental and neurological disorder associated with a de novo G375R variant of the tetrameric BK channel is unknown. Here, we address this question by recording from single BK channels expressed to mimic a G375R mutation heterozygous with a WT allele. Five differe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067970/ https://www.ncbi.nlm.nih.gov/pubmed/36995317 http://dx.doi.org/10.1085/jgp.202213302 |