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Confounding factors in profiling of locus-specific human endogenous retrovirus (HERV) transcript signatures in primary T cells using multi-study-derived datasets

BACKGROUND: Human endogenous retroviruses (HERV) are repetitive sequence elements and a substantial part of the human genome. Their role in development has been well documented and there is now mounting evidence that dysregulated HERV expression also contributes to various human diseases. While rese...

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Detalles Bibliográficos
Autores principales: Hamann, Martin V., Adiba, Maisha, Lange, Ulrike C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068191/
https://www.ncbi.nlm.nih.gov/pubmed/37013607
http://dx.doi.org/10.1186/s12920-023-01486-y