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Post‐transcriptional polyadenylation site cleavage maintains 3′‐end processing upon DNA damage

The recognition of polyadenylation signals (PAS) in eukaryotic pre‐mRNAs is usually coupled to transcription termination, occurring while pre‐mRNA is chromatin‐bound. However, for some pre‐mRNAs, this 3′‐end processing occurs post‐transcriptionally, i.e., through a co‐transcriptional cleavage (CoTC)...

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Detalles Bibliográficos
Autores principales: Sfaxi, Rym, Biswas, Biswendu, Boldina, Galina, Cadix, Mandy, Servant, Nicolas, Chen, Huimin, Larson, Daniel R, Dutertre, Martin, Robert, Caroline, Vagner, Stéphan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068322/
https://www.ncbi.nlm.nih.gov/pubmed/36762421
http://dx.doi.org/10.15252/embj.2022112358