The eukaryotic translation initiation factor eIF4E reprograms alternative splicing

Aberrant splicing is typically attributed to splice‐factor (SF) mutation and contributes to malignancies including acute myeloid leukemia (AML). Here, we discovered a mutation‐independent means to extensively reprogram alternative splicing (AS). We showed that the dysregulated expression of eukaryot...

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Detalles Bibliográficos
Autores principales: Ghram, Mehdi, Morris, Gavin, Culjkovic‐Kraljacic, Biljana, Mars, Jean‐Clement, Gendron, Patrick, Skrabanek, Lucy, Revuelta, Maria Victoria, Cerchietti, Leandro, Guzman, Monica L, Borden, Katherine L B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068332/
https://www.ncbi.nlm.nih.gov/pubmed/36843541
http://dx.doi.org/10.15252/embj.2021110496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068332/
https://www.ncbi.nlm.nih.gov/pubmed/36843541
http://dx.doi.org/10.15252/embj.2021110496

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