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The eukaryotic translation initiation factor eIF4E reprograms alternative splicing

Aberrant splicing is typically attributed to splice‐factor (SF) mutation and contributes to malignancies including acute myeloid leukemia (AML). Here, we discovered a mutation‐independent means to extensively reprogram alternative splicing (AS). We showed that the dysregulated expression of eukaryot...

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Detalles Bibliográficos
Autores principales:	Ghram, Mehdi, Morris, Gavin, Culjkovic‐Kraljacic, Biljana, Mars, Jean‐Clement, Gendron, Patrick, Skrabanek, Lucy, Revuelta, Maria Victoria, Cerchietti, Leandro, Guzman, Monica L, Borden, Katherine L B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068332/ https://www.ncbi.nlm.nih.gov/pubmed/36843541 http://dx.doi.org/10.15252/embj.2021110496

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