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Triglyceride induces DNA damage leading to monocyte death by activating caspase-2 and caspase-8

Monocytes are peripheral leukocytes that function in innate immunity. Excessive triglyceride (TG) accumulation causes monocyte death and thus can compromise innate immunity. However, the mechanisms by which TG mediates monocyte death remain unclear to date. Thus, this study aimed to elucidate the me...

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Detalles Bibliográficos
Autores principales: Jung, Byung Chul, Kim, Hyun-Kyung, Kim, Sung Hoon, Kim, Yoon Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068338/
https://www.ncbi.nlm.nih.gov/pubmed/36593108
http://dx.doi.org/10.5483/BMBRep.2022-0201