Cargando…

Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model

Renal fibrosis is the final manifestation of chronic kidney disease (CKD) regardless of etiology. Hypoxia-inducible factor-2 alpha (HIF-2α) is an important regulator of chronic hypoxia, and the late-stage renal tubular HIF-2α activation exerts protective effects against renal fibrosis. However, its...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Dal-Ah, Lee, Mi-Ran, Oh, Hyung Jung, Kim, Myong, Kong, Kyoung Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068344/
https://www.ncbi.nlm.nih.gov/pubmed/36404595
http://dx.doi.org/10.5483/BMBRep.2022-0145