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Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model
Renal fibrosis is the final manifestation of chronic kidney disease (CKD) regardless of etiology. Hypoxia-inducible factor-2 alpha (HIF-2α) is an important regulator of chronic hypoxia, and the late-stage renal tubular HIF-2α activation exerts protective effects against renal fibrosis. However, its...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068344/ https://www.ncbi.nlm.nih.gov/pubmed/36404595 http://dx.doi.org/10.5483/BMBRep.2022-0145 |