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Hollow-fibre system model of tuberculosis reproducibility and performance specifications for best practice in drug and combination therapy development

BACKGROUND: The hollow-fibre system model of tuberculosis (HFS-TB) has been endorsed by regulators; however, application of HFS-TB requires a thorough understanding of intra- and inter-team variability, statistical power and quality controls. METHODS: Three teams evaluated regimens matching those in...

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Detalles Bibliográficos
Autores principales: Gumbo, Tawanda, Srivastava, Shashikant, Deshpande, Devyani, Pasipanodya, Jotam G, Berg, Alexander, Romero, Klaus, Hermann, David, Hanna, Debra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068422/
https://www.ncbi.nlm.nih.gov/pubmed/36794692
http://dx.doi.org/10.1093/jac/dkad029