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Application of Novel Breast Biospecimen Cell-Type Adjustment Identifies Shared DNA Methylation Alterations in Breast Tissue and Milk with Breast Cancer–Risk Factors

BACKGROUND: DNA methylation patterning is cell-type–specific and altered DNA methylation is well established to occur early in breast carcinogenesis, affecting non-cancerous, histopathologically normal breast tissue. Previous work assessing risk factor–associated alterations to DNA methylation in br...

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Detalles Bibliográficos
Autores principales: Muse, Meghan E., Carroll, Connolly D., Salas, Lucas A., Karagas, Margaret R., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068446/
https://www.ncbi.nlm.nih.gov/pubmed/36780234
http://dx.doi.org/10.1158/1055-9965.EPI-22-0405