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Application of Novel Breast Biospecimen Cell-Type Adjustment Identifies Shared DNA Methylation Alterations in Breast Tissue and Milk with Breast Cancer–Risk Factors
BACKGROUND: DNA methylation patterning is cell-type–specific and altered DNA methylation is well established to occur early in breast carcinogenesis, affecting non-cancerous, histopathologically normal breast tissue. Previous work assessing risk factor–associated alterations to DNA methylation in br...
Autores principales: | Muse, Meghan E., Carroll, Connolly D., Salas, Lucas A., Karagas, Margaret R., Christensen, Brock C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068446/ https://www.ncbi.nlm.nih.gov/pubmed/36780234 http://dx.doi.org/10.1158/1055-9965.EPI-22-0405 |
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