Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling

Combinatorial molecular therapy in pancreatic ductal adenocarcinoma (PDAC) has yielded largely disappointing results in clinical testing to-date as a multitude of adaptive resistance mechanisms is making selection of patients via molecular markers that capture essential, intersecting signaling route...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Miermont, Anne M., Sable, Rushikesh, Quadri, Humair S., Mathews Griner, Lesley A., Martin, Scott E., Odzorig, Taivan, De, Soumita, Ferrer, Marc, Powers, Astin S., Hewitt, Stephen M., Rudloff, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Cancer Genes and Networks
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068447/
https://www.ncbi.nlm.nih.gov/pubmed/36790955
http://dx.doi.org/10.1158/1541-7786.MCR-21-1036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068447/
https://www.ncbi.nlm.nih.gov/pubmed/36790955
http://dx.doi.org/10.1158/1541-7786.MCR-21-1036

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