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Clonal hematopoiesis with DNMT3A mutation is associated with lower white matter hyperintensity volume

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) increases the risk of cerebrovascular events, while its association with cerebral white matter hyperintensity (WMH) is undemonstrated. We evaluated the effect of CHIP and its major driving mutations on cerebral WMH severity. METHODS:...

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Detalles Bibliográficos
Autores principales: Lee, Woo‐Jin, Jung, Keun‐Hwa, Song, Han, Lee, Heesun, Park, Hyo Eun, Koh, Youngil, Choi, Su‐Yeon, Park, Kyung‐Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068463/
https://www.ncbi.nlm.nih.gov/pubmed/36807865
http://dx.doi.org/10.1111/cns.14114