Exosomal miR‐3131 derived from endothelial cells with KRAS mutation promotes EndMT by targeting PICK1 in brain arteriovenous malformations

AIMS: To explore the underlying mechanism by which low‐frequency KRAS mutations result in extensive EndMT occurrence. METHODS: Exosomes derived from primarily cultured brain arteriovenous malformation (bAVMs) and human umbilical vein endothelial cells (HUVECs) transfected with KRAS(G12D), KRAS(WT),...

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Detalles Bibliográficos
Autores principales: He, Qiheng, Huo, Ran, Wang, Jie, Xu, Hongyuan, Zhao, Shaozhi, Zhang, Junze, Sun, Yingfan, Jiao, Yuming, Weng, Jiancong, Zhao, Jizong, Cao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068464/
https://www.ncbi.nlm.nih.gov/pubmed/36718590
http://dx.doi.org/10.1111/cns.14103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068464/
https://www.ncbi.nlm.nih.gov/pubmed/36718590
http://dx.doi.org/10.1111/cns.14103

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