Novel asymmetrical azines appending 1,3,4-thiadiazole sulfonamide: synthesis, molecular structure analyses, in silico ADME, and cytotoxic effect

Toward finding potential and novel anticancer agents, we designed and prepared novel differently substituted unsymmetrical azine-modified thiadiazole sulfonamide derivatives using the “combi-targeting approach”. An efficient procedure for synthesizing the designed compounds starts with 5-acetyl-3-N-...

Descripción completa

Detalles Bibliográficos
Autores principales: Bondock, Samir, Albarqi, Tallah, Shaaban, Ibrahim A., Abdou, Moaz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068595/
https://www.ncbi.nlm.nih.gov/pubmed/37020890
http://dx.doi.org/10.1039/d3ra00123g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068595/
https://www.ncbi.nlm.nih.gov/pubmed/37020890
http://dx.doi.org/10.1039/d3ra00123g

Ejemplares similares