Cargando…
Novel asymmetrical azines appending 1,3,4-thiadiazole sulfonamide: synthesis, molecular structure analyses, in silico ADME, and cytotoxic effect
Toward finding potential and novel anticancer agents, we designed and prepared novel differently substituted unsymmetrical azine-modified thiadiazole sulfonamide derivatives using the “combi-targeting approach”. An efficient procedure for synthesizing the designed compounds starts with 5-acetyl-3-N-...
Autores principales: | Bondock, Samir, Albarqi, Tallah, Shaaban, Ibrahim A., Abdou, Moaz M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068595/ https://www.ncbi.nlm.nih.gov/pubmed/37020890 http://dx.doi.org/10.1039/d3ra00123g |
Ejemplares similares
-
Tail-approach based design, synthesis, and cytotoxic evaluation of novel disubstituted and trisubstituted 1,3-thiazole benzenesulfonamide derivatives with suggested carbonic anhydrase IX inhibition mechanism
por: Bondock, Samir, et al.
Publicado: (2023) -
Synthesis and Antiviral Activity of 5‑(4‑Chlorophenyl)-1,3,4-Thiadiazole Sulfonamides
por: Chen, Zhuo, et al.
Publicado: (2010) -
Cytotoxic Properties of 1,3,4-Thiadiazole Derivatives—A Review
por: Janowska, Sara, et al.
Publicado: (2020) -
Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole N-glycosides
por: Alminderej, Fahad M., et al.
Publicado: (2019) -
Synthesis, Molecular Docking, In Silico ADME Predictions, and Toxicity Studies of N-Substituted-5-(4-Chloroquinolin-2-yl)-1,3,4-Thiadiazol-2-Amine Derivatives as COVID-19 Inhibitors
por: Hanaa S. Mohamed, et al.
Publicado: (2021)