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m(6)A methyltransferase METTL3 programs CD4(+) T-cell activation and effector T-cell differentiation in systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disorder in which excessive CD4(+) T-cell activation and imbalanced effector T-cell differentiation play critical roles. Recent studies have implied a potential association between posttranscriptional N6-methyladenosine (m(6)A) modifica...

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Detalles Bibliográficos
Autores principales: Lu, Shuang, Wei, Xingyu, Zhu, Huan, Hu, Zhi, Zheng, Meiling, Wu, Jiali, Zhao, Cheng, Yang, Shuang, Feng, Delong, Jia, Sujie, Zhao, Hongjun, Zhao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068720/
https://www.ncbi.nlm.nih.gov/pubmed/37013484
http://dx.doi.org/10.1186/s10020-023-00643-4