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m(6)A methyltransferase METTL3 programs CD4(+) T-cell activation and effector T-cell differentiation in systemic lupus erythematosus
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disorder in which excessive CD4(+) T-cell activation and imbalanced effector T-cell differentiation play critical roles. Recent studies have implied a potential association between posttranscriptional N6-methyladenosine (m(6)A) modifica...
Autores principales: | Lu, Shuang, Wei, Xingyu, Zhu, Huan, Hu, Zhi, Zheng, Meiling, Wu, Jiali, Zhao, Cheng, Yang, Shuang, Feng, Delong, Jia, Sujie, Zhao, Hongjun, Zhao, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068720/ https://www.ncbi.nlm.nih.gov/pubmed/37013484 http://dx.doi.org/10.1186/s10020-023-00643-4 |
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