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Redox metabolism maintains the leukemogenic capacity and drug resistance of AML cells

Rewiring of redox metabolism has a profound impact on tumor development, but how the cellular heterogeneity of redox balance affects leukemogenesis remains unknown. To precisely characterize the dynamic change in redox metabolism in vivo, we developed a bright genetically encoded biosensor for H(2)O...

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Detalles Bibliográficos
Autores principales: Huang, Dan, Zhang, Changcheng, Xiao, Ming, Li, Xie, Chen, Weicai, Jiang, Yu, Yuan, Yamin, Zhang, Yaping, Zou, Yejun, Deng, Lei, Wang, Yang, Sun, Yuying, Dong, Wenping, Zhang, Zhuo, Xie, Li, Yu, Zhuo, Chen, Chiqi, Liu, Ligen, Wang, Jing, Yang, Yi, Yang, Jie, Zhao, Yuzheng, Zheng, Junke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068762/
https://www.ncbi.nlm.nih.gov/pubmed/36947513
http://dx.doi.org/10.1073/pnas.2210796120