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The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

Increasing evidence has suggested that the HIV-1 capsid enters the nucleus in a largely assembled, intact form. However, not much is known about how the cone-shaped capsid interacts with the nucleoporins (NUPs) in the nuclear pore for crossing the nuclear pore complex. Here, we elucidate how NUP153...

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Detalles Bibliográficos
Autores principales: Shen, Qi, Kumari, Sushila, Xu, Chaoyi, Jang, Sooin, Shi, Jiong, Burdick, Ryan C., Levintov, Lev, Xiong, Qiancheng, Wu, Chunxiang, Devarkar, Swapnil C., Tian, Taoran, Tripler, Therese N., Hu, Yingxia, Yuan, Shuai, Temple, Joshua, Feng, Qingzhou, Lusk, C. Patrick, Aiken, Christopher, Engelman, Alan N., Perilla, Juan R., Pathak, Vinay K., Lin, Chenxiang, Xiong, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068764/
https://www.ncbi.nlm.nih.gov/pubmed/36943880
http://dx.doi.org/10.1073/pnas.2202815120