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circNEIL3 inhibits tumor metastasis through recruiting the E3 ubiquitin ligase Nedd4L to degrade YBX1

Distant metastasis is a major contributor to cancer-related mortality. However, the role of circRNAs in this process remains unclear. Herein, we profiled the circRNA expression in a cohort of 68 colorectal carcinoma (CRC) primary tumors and their paired liver metastatic lesions. By overlapping with...

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Detalles Bibliográficos
Autores principales: Chen, Shuang, Li, Ke, Guo, Jiawei, Chen, Hai-Ning, Ming, Yue, Jin, Yang, Xu, Fuyan, Zhang, Tingting, Yang, Yang, Ye, Zixia, Liu, Wenrong, Ma, Hulin, Cheng, Jian, Zhou, Jian-Kang, Li, Zhang, Shen, Shu, Dai, Lunzhi, Zhou, Zong-Guang, Xu, Heng, Peng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068820/
https://www.ncbi.nlm.nih.gov/pubmed/36961927
http://dx.doi.org/10.1073/pnas.2215132120