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Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies
Selection and development of monoclonal antibody (mAb) therapeutics against pathogenic viruses depends on certain functional characteristics. Neutralization potency, or the half-maximal inhibitory concentration (IC(50)) values, is an important characteristic of candidate therapeutic antibodies. Stru...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068833/ https://www.ncbi.nlm.nih.gov/pubmed/36961925 http://dx.doi.org/10.1073/pnas.2213690120 |