Lactate trafficking inhibition restores sensitivity to proteasome inhibitors and orchestrates immuno‐microenvironment in multiple myeloma

Metabolic changes of malignant plasma cells (PCs) and adaptation to tumour microenvironment represent one of the hallmarks of multiple myeloma (MM). We previously showed that MM mesenchymal stromal cells are more glycolytic and produce more lactate than healthy counterpart. Hence, we aimed to explor...

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Detalles Bibliográficos
Autores principales: Barbato, Alessandro, Giallongo, Cesarina, Giallongo, Sebastiano, Romano, Alessandra, Scandura, Grazia, Concetta, Saoca, Zuppelli, Tatiana, Lolicato, Marco, Lazzarino, Giacomo, Parrinello, Nunziatina, Del Fabro, Vittorio, Fontana, Paolo, Aguennoz, M'hammed, Li Volti, Giovanni, Palumbo, Giuseppe A., Di Raimondo, Francesco, Tibullo, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068934/
https://www.ncbi.nlm.nih.gov/pubmed/36794373
http://dx.doi.org/10.1111/cpr.13388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068934/
https://www.ncbi.nlm.nih.gov/pubmed/36794373
http://dx.doi.org/10.1111/cpr.13388

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