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Antigen‐specific TCR‐T cells from Rag2 gene‐deleted pluripotent stem cells impede solid tumour growth in a mouse model
The technology of adoptive transfer of T‐cell receptor (TCR) engineered T cells is wildly investigated as it has the potential to treat solid cancers. However, the therapeutic application of TCR‐T cells is hampered by the poor quality derived mainly from patients' peripheral blood, as well as h...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068938/ https://www.ncbi.nlm.nih.gov/pubmed/36592612 http://dx.doi.org/10.1111/cpr.13389 |