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Antigen‐specific TCR‐T cells from Rag2 gene‐deleted pluripotent stem cells impede solid tumour growth in a mouse model

The technology of adoptive transfer of T‐cell receptor (TCR) engineered T cells is wildly investigated as it has the potential to treat solid cancers. However, the therapeutic application of TCR‐T cells is hampered by the poor quality derived mainly from patients' peripheral blood, as well as h...

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Detalles Bibliográficos
Autores principales: Wu, Bingyan, Zhang, Qi, Hong, Pingshan, Liu, Lijuan, Peng, Huan, Xia, Chengxiang, Wang, Tongjie, Wang, Yao, Weng, Qitong, Liu, Xiaofei, Geng, Yang, Wang, Jinyong, Wu, Hongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068938/
https://www.ncbi.nlm.nih.gov/pubmed/36592612
http://dx.doi.org/10.1111/cpr.13389